General
Preferred name
TRIACETYLRESVERATROL
Synonyms
Acetyl-trans-resveratrol ()
Acetyl Resveratrol ()
P&D ID
PD000757
CAS
42206-94-0
Tags
available
nuisance
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION Triacetylresveratrol, an acetylated analog of Resveratrol. Triacetylresveratrol decreases the phosphorylation of STAT3 and NF-¦ÊB in a dose- and time- dependent manner in PANC-1 and BxPC-3 cells. Anticancer effects[1].
DESCRIPTION Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity,it inhibits the phosphorylation of STAT3 and NF??B, down-regulates Mcl-1, and up-regulates Bim and Puma in pancreatic cancer cells.
DESCRIPTION Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity,it inhibits the phosphorylation of STAT3 and NFκB, down-regulates Mcl-1, and up-regulates Bim and Puma in pancreatic cancer cells. (TargetMol Bioactive Compound Library)
Cell lines
2
Organisms
0
Compound Sets
6
Cayman Chemical Bioactives
26379
MedChem Express Bioactive Compound Library
HY-N1410
Nuisance compounds in cellular assays
Selleckchem Bioactive Compound Library
acetyl-resveratrol
TargetMol Bioactive Compound Library
T5668
The Spectrum Collection
External IDs
18
Properties
(calculated by RDKit )
Molecular Weight
354.11
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
0
Rotatable Bonds
5
Ring Count
2
Aromatic Ring Count
2
cLogP
3.63
TPSA
78.9
Fraction CSP3
0.15
Chiral centers
0.0
Largest ring
6.0
QED
0.46
Structural alerts
1
Nonspecific/NOS
Resveratrols
Nuisance compounds
Custom attributes
(extracted from source data)
Target
Mcl-1
NF-κB
STAT
STAT3
Pathway
Apoptosis
JAK/STAT Signaling
Stem Cells
Stem Cell/Wnt
NF-¦ÊB
Source data