General
Preferred name
CLIMBAZOLE
Synonyms
1-(P-chlorophenoxy)-1-imidazol-1-yl-3,3-dimethyl-2-butanone ()
BAY-e 6975 ()
NSC-759808 ()
Baypival ()
Climbazol ()
Crinipan ad ()
(±)-Climbazole-d4 ()
(±)-Climbazole ()
P&D ID
PD000725
CAS
38083-17-9
1185117-79-6
Tags
available
drug
Drug Status
approved
experimental
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Climbazole (BAY-e 6975) is a potent antifungal agent. Climbazole also is a potent inducer of rat hepatic cytochrome P450[2].
PRICE 29
DESCRIPTION Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff and eczema. Climbazole has shown a high in vitro and in vivo efficacy against Pityrosporum ovale that appears to play an important role in the pathogenesis of dandruff. (BOC Sciences Bioactive Compounds)
DESCRIPTION Climbazole (BAY-e 6975) is a broad-spectrum imidazole antifungal agent with anti-dandruff properties. (TargetMol Bioactive Compound Library)
Compound Sets
15
AdooQ Bioactive Compound Library
A16457
BOC Sciences Bioactive Compounds
climbazole-cas-38083-17-9-item-84-91405
Cayman Chemical Bioactives
27968
27616
ChEMBL Drugs
CHEMBL1437764
DrugBank
DB15580
DrugCentral
5064
DrugCentral Approved Drugs
5064
DrugMatrix
MedChem Express Bioactive Compound Library
HY-B1151
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
climbazole
TargetMol Bioactive Compound Library
T1403
The Spectrum Collection
External IDs
32
Properties
(calculated by RDKit )
Molecular Weight
292.1
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
2
cLogP
3.73
TPSA
44.12
Fraction CSP3
0.33
Chiral centers
1.0
Largest ring
6.0
QED
0.86
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology/virology
Anti-infection
MOA
Antibiotic
Cyp Enzyme Inducers
Antifungal
Member status
virtual
Target
Fungal
antibiotic
Source data