General
Preferred name
CYROMAZINE
Synonyms
N-cyclopropylmelamine ()
CGA-72662 ()
Cyromazin ()
Cyromazin,CGA-72662 ()
CGA 72662 ()
Neporex ()
Ciromazina ()
NSC-759268 ()
P&D ID
PD000677
CAS
66215-27-8
Tags
available
drug candidate
Drug Status
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Cyromazine (CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects. Cyromazine reduced the number of germ cells by interfering with the Ecdysone (HY-N0179) signaling pathway. Cyromazine induces renal toxicity attenuated and restored by green tea extract in rats[1][2][3][4][5].
PRICE 29
DESCRIPTION Cyromazine (CGA-72662) is an ectoparasiticide. Insect growth regulator. Specific activity against dipterous larvae. Cyromazine is a fda approved for use in livestock. (TargetMol Bioactive Compound Library)
Compound Sets
8
ChEMBL Drugs
CHEMBL1231107
Drug Repurposing Hub
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
HY-B1331
NPC Screening Collection
Selleckchem Bioactive Compound Library
cyromazine
TargetMol Bioactive Compound Library
T0845
The Spectrum Collection
External IDs
29
Properties
(calculated by RDKit )
Molecular Weight
166.1
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
1
cLogP
-0.39
TPSA
102.74
Fraction CSP3
0.5
Chiral centers
0.0
Largest ring
6.0
QED
0.55
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Parasite
Pathway
Metabolism
Anti-infection
Metabolic Enzyme/Protease
Source data