General
Preferred name
FLUVASTATIN SODIUM
Synonyms
Fluvastatin sodium salt ()
XU-62-320 ()
XU 62320 sodium ()
(3R,5S)-Fluvastatin (sodium) ()
Fluvastatin (sodium) ()
(3R,5S)-XU 62-320 ()
XU 62-320 ()
Vastin,XU-62-320 ()
Fluvastatin (XU-62-320) Sodium ()
Lescol ()
P&D ID
PD000673
CAS
94061-80-0
93957-55-2
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin sodium protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1][2][3].
DESCRIPTION (3R,5S)-Fluvastatin ((3R,5S)-XU 62-320) sodium is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1][2][3].
DESCRIPTION Fluvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. (Enamine Bioactive Compounds)
DESCRIPTION Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lowering agent. (TargetMol Bioactive Compound Library)
Compound Sets
8
AdooQ Bioactive Compound Library
A10403
Enamine Bioactive Compounds
EBC-13130
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
EOS100776
MedChem Express Bioactive Compound Library
HY-14664F
HY-14664A
Selleckchem Bioactive Compound Library
Fluvastatin-Sodium(Lescol)
TargetMol Bioactive Compound Library
T1487
The Spectrum Collection
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
433.17
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
8
Ring Count
3
Aromatic Ring Count
3
cLogP
0.3
TPSA
85.52
Fraction CSP3
0.29
Chiral centers
2.0
Largest ring
6.0
QED
0.5
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Apoptosis
Autophagy
Metabolism
Metabolic Enzyme/Protease
MOA
HMG-CoA Reductase inhibitor
Target
HMG-CoA Reductase (HMGCR)
Ferroptosis
HMG-CoA Reductase
HMGCR
Source data