General
Preferred name
SUCCIMER
Synonyms
2,3-DIMERCAPTOSUCCINIC ACID ()
DMSA ()
Dimercaptosuccinic acid ()
meso-2,3-Dimercaptosuccinic Acid ()
DMSA, meso-2,3-dimercaptosuccinic acid ()
RO 1-7977 ()
Chemet ()
DMS-A ()
Dim-Sa ()
P&D ID
PD000656
CAS
304-55-2
Tags
nuisance
natural product
drug
available
Approved by
FDA
First approval
1991
Drug Status
approved
Drug indication
Diagnostic Aid
Metal intoxication
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
19
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
MedChem Express Bioactive Compound Library
NPC Screening Collection
Nuisance compounds in cellular assays
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
28
Properties
(calculated by RDKit )
Molecular Weight
181.97
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
4
Rotatable Bonds
3
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.25
TPSA
74.6
Fraction CSP3
0.5
Chiral centers
2.0
Largest ring
0.0
QED
0.45
Structural alerts
1
Chelation
Pb
Nuisance compounds in cellular assays
Related compounds
Custom attributes
(extracted from source data)
Target
Cadmium
Lead
Mercury
DNMT1
Indication
metal toxicity
MOA
chelating agent
Source data
