General
Preferred name
THIOSTREPTON
Synonyms
P&D ID
PD000625
CAS
1393-48-2
Tags
drug candidate
natural product
available
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Immunomodulator; reduces production of pro-inflammatory cytokines (Tocris Bioactive Compound Library)
Compound Sets
5
DrugMAP
DML7Y1R
JUMP-Target 1 Compound Set
101290202
ReFrame library
The Spectrum Collection
Tocris Bioactive Compound Library
3267
External IDs
16
Properties
(calculated by RDKit )
Molecular Weight
1663.49
Hydrogen Bond Acceptors
31
Hydrogen Bond Donors
17
Rotatable Bonds
12
Ring Count
10
Aromatic Ring Count
5
cLogP
0.77
TPSA
562.74
Fraction CSP3
0.43
Chiral centers
17.0
Largest ring
27.0
QED
0.06
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Primary Target
DNA, RNA and Protein Synthesis
MOA
Inhibitor
Target
FOXM1
Source data