General
Preferred name
N,N'-Dicyclohexylurea
Synonyms
DICYCLOHEXYLUREA ()
DCU ()
Dicyclohexylcarbodiamide ()
NSC 17013 ()
1,3-DICYCLOHEXYLUREA ()
N,N'-dicyclohexyl-urea ()
P&D ID
PD000612
CAS
2387-23-7
Tags
available
drug candidate
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 1,3-Dicyclohexylurea (DCU) is an orally active and potent sEH (soluble epoxide hydrolase) inhibitor. Oral Delivery of 1,3-Dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive Rats[1].
PRICE 29
DESCRIPTION 1,3-Dicyclohexylurea is an inhibitor of bifunctional epoxide hydrolase 2. (Enamine Bioactive Compounds)
DESCRIPTION N,N'-Dicyclohexylurea (AURORA KA-3582) is a soluble epoxide hydrolase (sEH) inhibitor. (TargetMol Bioactive Compound Library)
Compound Sets
8
Cayman Chemical Bioactives
10004971
CZ-OPENSCREEN Bioactive Library
DrugMAP
DMLVMJH
Enamine Bioactive Compounds
EBC-03642
EU-OPENSCREEN Bioactive Compound Library
EOS102270
MedChem Express Bioactive Compound Library
HY-W013989
TargetMol Bioactive Compound Library
T23044
The Spectrum Collection
External IDs
32
Properties
(calculated by RDKit )
Molecular Weight
224.19
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
0
cLogP
2.95
TPSA
41.13
Fraction CSP3
0.92
Chiral centers
0.0
Largest ring
6.0
QED
0.74
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
sEH
epoxide hydrolase
Pathway
Metabolism
Metabolic Enzyme/Protease
Source data