General
Preferred name
N-PHENYLANTHRANILIC ACID
Synonyms
2-Anilinobenzoic acid ()
diphenylamine-2-carboxylic acid ()
2-(Phenylamino)benzoic acid ()
FENAMIC ACID ()
N-Phenylanthranilic acid, 2-(Phenylamino)benzoic acid, 2-Anilinobenzoic acid, Diphenylamine-2-carboxylic acid ()
2-Phenylamino-Benzoic Acid ()
2-(Phenylamino)Benzoic Acid ()
N-Phenylanthranilic Acid ()
NSC-215211 ()
P&D ID
PD000595
CAS
91-40-7
Tags
available
drug candidate
Drug indication
Discovery agent
pancreatic carcinoma
Drug Status
investigational
Max Phase
1.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Fenamic acid (N-Phenylanthranilic acid, NPAA) is an orally active chloride channel blocker. Fenamic acid is the basic constituent of non-steroidal anti-inflammatory agents (NSAIA), and derives into mefenamic, tofenacin, flufenac acid and melofenac acid. Fenamic acid also acts as antibacterial and analgesic agent[1]-[6].
PRICE
29
DESCRIPTION
N-Phenylanthranilic acid is a chloride channel blocker. N-Phenylanthranilic acid serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs).
(Enamine Bioactive Compounds)
DESCRIPTION
Cl- channel blocker
(LOPAC library)
DESCRIPTION
Fenamic acid (N-Phenylanthranilic acid) is a chloride channel blocker that causes renal papillary necrosis in rats. Fenamic acid serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), including flufenamic acid, tolfenamic acid, mefenamic acid, and meclofenamic acid.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
14
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugMAP
Enamine Bioactive Compounds
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
LOPAC library
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
34
Molecular Weight
213.08
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
2
cLogP
3.13
TPSA
49.33
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.82
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Chloride channel
Immunology & Inflammation related
Pathway
Membrane Transporter/Ion Channel
Source data
