General
Preferred name
AMLODIPINE BESYLATE
Synonyms
Amlodipine benzenesulfonate ()
UK-48340 ()
FCP-3P1 ()
Amlodipine (besylate) ()
Amlodipine (benzenesulfonate) ()
AMLODIPINE ()
UK-48340-26 ()
Amlodipine besylate component of tekamlo ()
Amlodipine besylate component of dafiro-hct amlodipine besilate ()
Norliqva ()
Lodipressin ()
Amlodipine besylate component of imprida amlodipine besilate ()
Amlodipine besylate component of lotrel ()
Amlodipine besylate component of exforge ()
Amlodipine besylate component of tribenzor ()
Amlodipine besylate component of twynsta ()
Amlor ()
Amlodipine besylate component of caduet ()
Amlodipine besylate component of onduarp ()
Antacal ()
Amlodipine besylate component of exforge hct ()
Amlodipine besylate component of amturnide ()
Amlodipine (as besilate) ()
Monopina ()
Amlodipine besylate component of exforge-hct amlodipine besilate ()
Amlodipine besylate component of prestalia ()
NSC-758922 ()
Amlodipine besylate component of exforge amlodipine besilate ()
Amlodipine besylate component of dafiro amlodipine besilate ()
Amlodipine besylate component of azor ()
Amlodipine besylate component of consensi ()
Amlodipine besylate component of copalia ()
Amlodipine Besilate ()
Norvasc ()
Amlodipine besylate component of amlessa ()
Amlodipine besylate component of imprida-hct amlodipine besilate ()
UK-48,340-26 ()
P&D ID
PD000570
CAS
88150-42-9
111470-99-6
Tags
available
drug
Drug indication
Arteriosclerosis
Hypertension
Drug Status
approved
Max Phase
4.0
First approval
1992
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Amlodipine besylate (Amlodipine benzenesulfonate), an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine besylate can be used for the research of high blood pressure and cancer[1][2][3].
DESCRIPTION
Amlodipine is a calcium channel blocker used to treat hypertension and angina.
(Enamine Bioactive Compounds)
DESCRIPTION
Ca2+ channel blocker (L-type)
(Tocriscreen Plus)
DESCRIPTION
Ca2+ channel blocker (L-type)
(Tocriscreen Total)
DESCRIPTION
Amlodipine Besylate(Amlodipine benzenesulfonate) is a long-lasting calcium channel blocker.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Amlodipine (UK-48340) is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties.
(TargetMol Bioactive Compound Library)
DESCRIPTION
Na+ channel blocker; antiarrhythmic agent
(Tocris Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
15
Axon Medchem Screening Library
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
DrugMAP
Enamine Bioactive Compounds
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
Selleckchem Bioactive Compound Library
The Spectrum Collection
Tocris Bioactive Compound Library
Tocriscreen Plus
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
28
Molecular Weight
566.15
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
3
Rotatable Bonds
9
Ring Count
3
Aromatic Ring Count
2
cLogP
3.2
TPSA
154.25
Fraction CSP3
0.31
Chiral centers
1.0
Largest ring
6.0
QED
0.23
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
Ion Channels
Target
Calcium Channel
Ca channel blocker
Primary Target
CaV1.x Channels (L-type)
MOA
Blocker
Pathway
Membrane Transporter/Ion Channel
Neuronal Signaling
Metabolism
Source data
