General
Preferred name
ALMOTRIPTAN
Synonyms
LAS 31416 ()
PNU180638 ()
ALMOTRIPTAN MALATE ()
Almotriptan malate (Axert) ()
Almogran ()
Almotriptan (malate) ()
LAS-31416 ()
NSC-760092 ()
LAS 31416 D,L-MALATE ACID ()
Almotriptan d,l-hydrogenmalate ()
LAS-31416-D,L-MALATE-ACID ()
Axert ()
PNU-180638E ()
Almotriptan maleate ()
LAS-31416 D,L-Malate acid ()
P&D ID
PD000568
CAS
154323-57-6
181183-52-8
Tags
available
drug
Approved by
FDA
First approval
2001
Drug Status
investigational
approved
Drug indication
Migraine
Antimigraine
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Almotriptan is a triptan (tryptamine-based) drug that acts as an agonist of serotonin 5-HT1B/1D receptors . It is used to treat migraine headaches but does not prevent or cure them. (GtoPdb)
Compound Sets
19
AdooQ Bioactive Compound Library
A11799
Cayman Chemical Bioactives
25646
ChEMBL Approved Drugs
CHEMBL1505
CHEMBL1200521
ChEMBL Drugs
CHEMBL1505
CHEMBL1200521
Drug Repurposing Hub
DrugBank
DB00918
DrugBank Approved Drugs
DB00918
DrugCentral
128
DrugCentral Approved Drugs
128
DrugMAP
DM7I64Z
DrugMAP Approved Drugs
DM7I64Z
DrugMatrix
Guide to Pharmacology
7110
MedChem Express Bioactive Compound Library
HY-B0383A
HY-B0383
NCATS Inxight Approved Drugs
1O4XL5SN61
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
almotriptan-malate-axert
TargetMol Bioactive Compound Library
T2317
External IDs
51
Properties
(calculated by RDKit )
Molecular Weight
335.17
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
6
Ring Count
3
Aromatic Ring Count
2
cLogP
2.2
TPSA
56.41
Fraction CSP3
0.53
Chiral centers
0.0
Largest ring
6.0
QED
0.88
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Target
5-HT1B/1D
HTR1B, HTR1D
5-HT Receptor
Indication
migraine headache
MOA
serotonin receptor agonist
Therapeutic Class
Antimigraine Agents
Source data