General
Preferred name
CEFTIBUTEN
Synonyms
Ceftibuten (dihydrate) ()
Ceftibuten hydrate ()
Sch-39720 (dihydrate) ()
Ceftibuten dihydrate ()
Sch-39720 dihydrate ()
Sch 39720 ()
Seftem ()
Ceftibutin ()
SCH-39720 ()
NSC-758925 ()
7432-S ()
ACHN-383 ()
Cedax ()
ACHN383 ()
Ceftibuten (hydrate) ()
P&D ID
PD000565
CAS
118081-34-8
97519-39-6
Tags
natural product
drug
available
Approved by
FDA
First approval
1995
Drug Status
investigational
approved
Drug indication
Antibacterial
Chronic bronchitis
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Ceftibuten is a semisynthetic, third generation cephalosporin and belongs to the β-lactam class of antibacterial compounds . (GtoPdb)
INDICATION Indicated for the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
PHARMACODYNAMICS Ceftibuten is an antibiotic with bactericidal actions.
Compound Sets
17
Cayman Chemical Bioactives
25334
ChEMBL Approved Drugs
CHEMBL1605
ChEMBL Drugs
CHEMBL1605
Drug Repurposing Hub
DrugBank
DB01415
DrugBank Approved Drugs
DB01415
DrugCentral
562
DrugCentral Approved Drugs
562
DrugMAP
DMWV2AG
DrugMAP Approved Drugs
DMWV2AG
Guide to Pharmacology
12029
MedChem Express Bioactive Compound Library
HY-B0698A
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
ceftibuten-dihydrate
The Spectrum Collection
External IDs
49
Properties
(calculated by RDKit )
Molecular Weight
410.04
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
4
Rotatable Bonds
6
Ring Count
3
Aromatic Ring Count
1
cLogP
-0.05
TPSA
162.92
Fraction CSP3
0.27
Chiral centers
2.0
Largest ring
6.0
QED
0.37
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Bacterial
antibiotic
Beta-lactamase
Pathway
Anti-infection
Disease Area
pulmonary, otolaryngology
Indication
bronchitis, otitis, pharyngitis, tonsillitis
MOA
bacterial cell wall synthesis inhibitor
Therapeutic Class
Antibiotics
Source data