General
Preferred name
HUPERZINE A
Synonyms
HupA ()
(-)-Huperzine A ()
(-)-Huperzine A (HupA) ()
(?)-Huperzine A ()
P&D ID
PD000542
CAS
102518-79-6
Tags
available
drug
Drug indication
Alzheimer disease
Drug Status
approved
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Compound Sets
9
Cayman Chemical Bioactives
14620
Drug Repurposing Hub
DrugBank
DB04864
DrugBank Approved Drugs
DB04864
DrugMAP
DMMAWLU
DrugMAP Approved Drugs
DMMAWLU
MedChem Express Bioactive Compound Library
HY-17387
Selleckchem Bioactive Compound Library
(-)-Huperzine-A
The Spectrum Collection
External IDs
36
Properties
(calculated by RDKit )
Molecular Weight
242.14
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
3
Aromatic Ring Count
1
cLogP
2.0
TPSA
58.88
Fraction CSP3
0.4
Chiral centers
2.0
Largest ring
6.0
QED
0.68
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
AChR inhibitor
Acetylcholinesterase inhibitor
Pathway
Neuroscience
Apoptosis
Membrane Transporter/Ion Channel
Neuronal Signaling
Target
AChE (G4 form)
AChE
Cholinesterase (ChE)
iGluR
AChR,GluR
Source data