General
Preferred name
CROTAMITON
Synonyms
Crotamitone ()
Eurax ()
Veteusan ()
N-Ethyl-o-crotonotoluidide483-63-6 ()
N-Ethyl-o-crotonotoluidide ()
Crotan ()
NSC-758951 ()
N-ethyl-o-crotonotoluidide ()
N-ethylcrotono-o-toluidide ()
P&D ID
PD000529
CAS
483-63-6
Tags
natural product
drug
available
Drug Status
approved
Max Phase
Phase 4
Drug indication
Scabicide
First approval
1949
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Crotamiton is a drug, available as a cream or lotion for topical use only, that is used both as a scabicidal (for treating scabies) and as a general antipruritic (anti-itching drug). (GtoPdb)
DESCRIPTION Crotamiton is a general antipruritic agent for treating scabies. (BOC Sciences Bioactive Compounds)
Compound Sets
16
AdooQ Bioactive Compound Library
A10243
BOC Sciences Bioactive Compounds
n-ethyl-o-crotonotoluidide-cas-483-63-6-69482
Cayman Chemical Bioactives
23943
ChEMBL Approved Drugs
CHEMBL1200709
ChEMBL Drugs
CHEMBL1200709
Concise Guide to Pharmacology 2021/22
11165
Concise Guide to Pharmacology 2023/24
11165
Drug Repurposing Hub
Guide to Pharmacology
11165
MedChem Express Bioactive Compound Library
HY-B1177
NIH Clinical Collections (NCC)
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
Crotamiton
TargetMol Bioactive Compound Library
T0376
The Spectrum Collection
External IDs
25
Properties
(calculated by RDKit )
Molecular Weight
203.13
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
0
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
2.92
TPSA
20.31
Fraction CSP3
0.31
Chiral centers
0.0
Largest ring
6.0
QED
0.69
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Microbiology&virology
Anti-infection
Target
Parasite
Indication
scabies
MOA
antipruritic
Solubility
Soluble in DMSO
Source data