General
Preferred name
PAEONOL
Synonyms
Peonol ()
Paeonol (Peonol) ()
P&D ID
PD000445
CAS
552-41-0
Tags
available
drug candidate
Drug Status
investigational
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Paeonol is an active extraction from the root of Paeonia suffruticosa, Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 ¦ÌM and 42.5 ¦ÌM, respectively.
PRICE 29
DESCRIPTION Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 ??M and 42.5 ??M, respectively.
DESCRIPTION Paeonol is a phenol that has been found in Paeonia and has diverse biological activities. It can effectively block voltage-operated Ca2+ channels (VOCCs) to exert calcium antagonism, IC50 = 17 µM. (Enamine Bioactive Compounds)
DESCRIPTION Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively. (TargetMol Bioactive Compound Library)
Compound Sets
10
AdooQ Bioactive Compound Library
A10690
Cayman Chemical Bioactives
19862
Drug Repurposing Hub
DrugBank
DB16830
Enamine Bioactive Compounds
EBC-13745
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
HY-N0159
Selleckchem Bioactive Compound Library
Paeonol(Peonol)
TargetMol Bioactive Compound Library
T2900
The Spectrum Collection
External IDs
33
Properties
(calculated by RDKit )
Molecular Weight
166.06
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
1.6
TPSA
46.53
Fraction CSP3
0.22
Chiral centers
0.0
Largest ring
6.0
QED
0.68
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Autophagy
Metabolism
Neuroscience
Neuronal Signaling
MOA
anti-inflammatory agent
Target
Monoamine Oxidase
MAO
MAO-A
MAO-B
Source data