General
Preferred name
HALOTHANE
Synonyms
Narcotane ()
Anestan ()
2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE ()
Halothanum ()
NSC-143490 ()
FREON 123B1 ()
Rhidialothan ()
Fluothane ()
P&D ID
PD000413
CAS
151-67-7
Tags
available
drug
Approved by
FDA
First approval
1958
Drug Status
withdrawn
approved
vet_approved
Drug indication
Anesthetic (inhalation)
Anaesthesia
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Halothane is a volatile anaesthetic which causes rapid anaesthesia, but requires use of additional nitrous oxide and/or neuromuscular blocking agents to be fully effective.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
21
ChEMBL Approved Drugs
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
31
Molecular Weight
195.89
Hydrogen Bond Acceptors
0
Hydrogen Bond Donors
0
Rotatable Bonds
0
Ring Count
0
Aromatic Ring Count
0
cLogP
2.51
TPSA
0.0
Fraction CSP3
1.0
Chiral centers
1.0
Largest ring
0.0
QED
0.52
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Membrane Transporter/Ion Channel
Neuroscience
Target
Glycine receptor
GABAR
NMDA Receptor
Potassium Channel
ATC
N01AB01
Therapeutic Class
Anesthetics
Source data
