General
Preferred name
LEVOCARNITINE
Synonyms
CARNITINE ()
L-carnitine ()
L(-)-Carnitine ()
Levacecarnine HCL ()
(R)-Carnitine ()
Levocarnitine,Carnitor, vitamin BT, Karnitin,L(-)-Carnitine ()
Carnitor Sf ()
Carnitine dl-form hydrochloride ()
Carnitine ()
Biocarn ()
Vitamin Bt ()
Carnitine hydrochloride, dl- ()
Oristar lch ()
Bicarnesine ()
Levocarnitine Chloride ()
Carnitine hydrochloride ()
Levocarnitine hcl ()
Carnitine hcl ()
Carnitor ()
NSC-759132 ()
Levocarnitine hydrochloride ()
DL-Carnitine hydrochloride ()
L-carnitine ()
P&D ID
PD000410
CAS
44985-71-9
541-15-1
Tags
available
drug
Approved by
FDA
First approval
1985
Drug Status
investigational
approved
Drug indication
Nutritional deficiency
Replenisher (carnitine)
Cognitive impairment
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
ABSORPTION Absolute bioavailability is 15% (tablets or solution).; Time to maximum plasma concentration was found to be 3.3 hours.
ROE Following a single intravenous dose, 73.1 +/- 16% of the dose was excreted in the urine during the 0-24 hour interval. ; Post administration of oral carnitine supplements, in addition to a high carnitine diet, 58-65% of the administered radioactive dose was recovered from urine and feces in 5-11 days. ;
HALF-LIFE 17.4 hours (elimination) following a single intravenous dose.;
Compound Sets
21
Cayman Chemical Bioactives
21489
ChEMBL Approved Drugs
CHEMBL1149
ChEMBL Drugs
CHEMBL1149
Concise Guide to Pharmacology 2017/18
4780
Concise Guide to Pharmacology 2019/20
4780
Concise Guide to Pharmacology 2021/22
4780
Concise Guide to Pharmacology 2023/24
4780
DrugBank
DB00583
DrugBank Approved Drugs
DB00583
DrugCentral
513
DrugCentral Approved Drugs
513
DrugMAP
DMJBOCR
DrugMAP Approved Drugs
DMJBOCR
Guide to Pharmacology
4780
MedChem Express Bioactive Compound Library
HY-B0399
NCATS Inxight Approved Drugs
0G389FZZ9M
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
L-carnitine(Levocarnitine)
TargetMol Bioactive Compound Library
T0846
The Spectrum Collection
External IDs
39
Properties
(calculated by RDKit )
Molecular Weight
161.11
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
0
Aromatic Ring Count
0
cLogP
-1.81
TPSA
60.36
Fraction CSP3
0.86
Chiral centers
1.0
Largest ring
0.0
QED
0.49
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolism
Metabolic Enzyme/Protease
Target
FAS
Endogenous Metabolite
Source data