General
Preferred name
PRALIDOXIME CHLORIDE
Synonyms
2-PAM chloride ()
2-Pyridinealdoxime methochloride ()
2-PAM (chloride) ()
Pralidoxime (chloride) ()
NSC-164614 ()
Protopam ()
Contrathion ()
Duodote ()
Protopam Chloride ()
Pralidoxime chloride (autoinjector) ()
2-PAM ()
P&D ID
PD000402
CAS
51-15-0
Tags
available
drug
Drug indication
Poisoning due to pesticides and chemicals
Cholinesterase Reactivator
Drug Status
approved
Max Phase
Phase 4
First approval
1964
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
12
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
32
Properties
(calculated by RDKit )
Molecular Weight
172.04
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
1
cLogP
-2.68
TPSA
36.47
Fraction CSP3
0.14
Chiral centers
0.0
Largest ring
6.0
QED
0.21
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Neuroscience
Neuronal Signaling
Target
AChE
Cholinesterase (ChE)
AChR
MOA
AChR antagonist
Source data
