General
Preferred name
PARAMETHADIONE
Synonyms
Paramethadionum ()
Paramethadione ()
Isoethadione ()
NSC-760129 ()
Paradione ()
P&D ID
PD000397
CAS
115-67-3
Tags
natural product
drug
available
Approved by
FDA
First approval
1949
Drug Status
approved
withdrawn
Drug indication
Fetal trimethadione syndrome
Seizure disorder
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Paramethadione is an anticonvulsant drug.
(GtoPdb)
DESCRIPTION
This active molecular is an an antiepileptic and anticonvulsant agent. It is associated with fetal trimethadione syndrome that is also called as paramethadione syndrome.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
16
BOC Sciences Bioactive Compounds
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
NPC Screening Collection
ReFrame library
The Spectrum Collection
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
25
Molecular Weight
157.07
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
0
cLogP
0.76
TPSA
46.61
Fraction CSP3
0.71
Chiral centers
1.0
Largest ring
5.0
QED
0.56
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
ATC
N03AC01
Therapeutic Class
Anticonvulsants
Solubility
Soluble in DMSO
Source data
