General
Preferred name
TAURINE
Synonyms
Taurine, monopotassium salt ()
2-Aminoethanesulfonic Acid ()
Taurate ()
Ethanesulfonic acid, 2-amino- ()
O-Due ()
NSC-32428 ()
FEMA NO. 3813 ()
Aminoethylsulfonic Acid ()
Taurine-d4 ()
P&D ID
PD000392
CAS
342611-14-7
107-35-7
Tags
natural product
drug
available
Approved by
PMDA
FDA
First approval
2019
Drug Status
nutraceutical
approved
Drug indication
Discovery agent
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Endogenous potentiator of NMDA receptors (Tocris Bioactive Compound Library)
DESCRIPTION Non-selective endogenous agonist at glycine receptors (LOPAC library)
Compound Sets
25
AdooQ Bioactive Compound Library
A10892
Cayman Chemical Bioactives
27031
35211
ChEMBL Approved Drugs
CHEMBL239243
ChEMBL Drugs
CHEMBL239243
Concise Guide to Pharmacology 2017/18
2379
Concise Guide to Pharmacology 2019/20
2379
Concise Guide to Pharmacology 2021/22
2379
Concise Guide to Pharmacology 2023/24
2379
Drug Repurposing Hub
DrugBank
DB01956
DrugBank Approved Drugs
DB01956
DrugCentral
4486
DrugCentral Approved Drugs
4486
DrugMAP
DMVW7N3
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
2379
LOPAC library
MedChem Express Bioactive Compound Library
HY-B0351
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
Taurine
TargetMol Bioactive Compound Library
T0022
The Spectrum Collection
Tocris Bioactive Compound Library
0209
External IDs
54
Properties
(calculated by RDKit )
Molecular Weight
125.01
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
0
Aromatic Ring Count
0
cLogP
-1.17
TPSA
80.39
Fraction CSP3
1.0
Chiral centers
0.0
Largest ring
0.0
QED
0.46
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolism
Autophagy
Metabolic Enzyme/Protease
Target
LDL
VLDL
Endogenous Metabolite
Primary Target
Glycine Receptors
MOA
Agonist
Antioxidant
Indication
anxiety, irritability, sleeplessness
Source data