General
Preferred name
Phylloquinone
Synonyms
PHYTONADIONE [5mM] ()
phytomenadione ()
PHYTONADIONE ()
Phyllohydroquinone ()
Vitamin K1 ()
Phyllohydroquinone, Phylloquinone, Phytomenadione, Phytonadione ()
Vitamin K1 ()
Kanavit ()
Konakion MM ()
Orakay ()
Phylloquinone e-form ()
Phytomenadione ()
NSC-270681 ()
Aquamephyton ()
Konakion ()
Konakion MM Paed ()
Vitamin K 1 ()
Phytonadione component of vitaped ()
Neokay ()
Mephyton ()
Fitomenadiona ()
P&D ID
PD000381
CAS
10485-69-5
84-80-0
79083-00-4
Tags
available
drug
Approved by
FDA
First approval
1982
2000
Drug indication
Vitamin K deficiency
Bleeding disorder
Postmenopausal osteoporosis
Drug Status
approved
investigational
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.
DESCRIPTION
Vitamin K1 a fat-soluble, naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.
(Enamine Bioactive Compounds)
DESCRIPTION
Vitamin K1 (Phylloquinone) a fat-soluble, naturally occurring vitamin with antihemorrhagic and prothrombogenic activity.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
18
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Enamine Bioactive Compounds
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
54
Molecular Weight
450.35
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
14
Ring Count
2
Aromatic Ring Count
1
cLogP
9.16
TPSA
34.14
Fraction CSP3
0.61
Chiral centers
2.0
Largest ring
6.0
QED
0.26
Structural alerts
1
quinone_A(370)
[!#6&!#1]=[#6]1[#6]=,:[#6][#6](=[!#6&!#1])[#6]=,:[#6]1
PAINS Family A
Related compounds
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
GGCX
Osteocalcin
BGLAP, GGCX
Vitamin
Member status
member
MOA
Cytochrome P450 CYP4F2 Inhibitors
Vitamin K analogs
Indication
vitamin K deficiency, anticoagulation reversal
Therapeutic Class
Vitamins
Pathway
Metabolism
Metabolic Enzyme/Protease
Source data
