General
Preferred name
BUCETIN
Synonyms
N-(beta-hydroxybutyryl)-p-phenetidine ()
3-Hydroxy-p-butyrophenetidide ()
NSC-759243 ()
Bucetina ()
Betadid ()
3-hydroxy-4-butyrophenetidide ()
Bucetine ()
NSC-320045 ()
P&D ID
PD000284
CAS
1083-57-4
Tags
available
drug
Drug Status
approved
withdrawn
Max Phase
4.0
Drug indication
Pain
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Bucetin (3-Hydroxy-p-butyrophenetidide) is an antipyretic compound and can also be used in pain relief studies.
PRICE 29
DESCRIPTION Bucetin, a phenacetin analog, has antipyretic and analgesic effect. It has been discontinued for showing renal toxicity. (BOC Sciences Bioactive Compounds)
DESCRIPTION Bucetin (3-Hydroxy-p-butyrophenetidide) is a pharmaceutical drug that functions as an analgesic and antipyretic. It was withdrawn from use in 1986 due to renal toxicity. (TargetMol Bioactive Compound Library)
Compound Sets
14
BOC Sciences Bioactive Compounds
bucetin-cas-1083-57-4-item-54134
ChEMBL Approved Drugs
CHEMBL1697856
ChEMBL Drugs
CHEMBL1697856
DrugBank
DB13278
DrugBank Approved Drugs
DB13278
DrugCentral
413
DrugCentral Approved Drugs
413
MedChem Express Bioactive Compound Library
HY-B0906
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
bucetin
TargetMol Bioactive Compound Library
T0442
The Spectrum Collection
Withdrawn 2.0
w83
External IDs
26
Properties
(calculated by RDKit )
Molecular Weight
223.12
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
5
Ring Count
1
Aromatic Ring Count
1
cLogP
1.79
TPSA
58.56
Fraction CSP3
0.42
Chiral centers
1.0
Largest ring
6.0
QED
0.8
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
ATC
N02BE04
Toxicity type
renal
Solubility
DMSO:35mg/mL
Source data