General
Preferred name
OXYPHENONIUM BROMIDE
Synonyms
Spasmophen ()
Oxifenon ()
Oxyfenon ()
Atrenyl ()
Oxyphenon ()
Oxyphenonium Bromide ()
Oxyphenonium (bromide) ()
NSC-759248 ()
Antrenyl ()
Antrenil ()
Spasmodin ()
C-5473 ()
Bromuro de oxifenonio ()
Bromure d'oxyphenonium ()
BA-5473 ()
P&D ID
PD000274
CAS
50-10-2
Tags
available
drug
Drug Status
approved
Max Phase
4.0
First approval
1982
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
32
DESCRIPTION
Oxyphenonium is an anticholinergic drug, a medication that reduces the effect of acetylcholine. Oxyphenonium is used to treat or prevent spasm in the muscles of the gastrointestinal tract in the irritable bowel syndrome.
(Enamine Bioactive Compounds)
DESCRIPTION
Oxyphenonium bromide is an antimuscarinic. It is a quaternary ammonium anticholinergic agent with peripheral side effects similar to those of atropine. It is used as an adjunct in the treatment of gastric and duodenal ulcer to relieve visceral spasms. It has been used in a study to assess masking mechanisms of bitter taste of drugs and investigate stoichiometric and microenvironmental effects on hydrolysis of propantheline in cyclodextrin solutions. It has also been used in the form of eye drops for mydriatic effect. It has been listed.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Oxyphenonium bromide (Oxyfenon) shows anticholinergic activity and can be used for research on the treatment of gastric and duodenal ulcers and for the relief of visceral spasms.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
13
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
CeMM library of unique drugs (CLOUD)
ChEMBL Approved Drugs
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
DrugMatrix
Enamine Bioactive Compounds
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
NIH Clinical Collections (NCC)
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
15
Molecular Weight
427.17
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
8
Ring Count
2
Aromatic Ring Count
1
cLogP
0.49
TPSA
46.53
Fraction CSP3
0.67
Chiral centers
1.0
Largest ring
6.0
QED
0.48
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
muscarinic acetylcholine receptor antagonist
Target
Muscarinic acetylcholine receptor M1
Muscarinic acetylcholine receptor M3
mAChR
Pathway
GPCR/G protein
Neuronal Signaling
Solubility
Soluble in DMSO, not in water
Source data
