General
Preferred name
ORNIDAZOLE
Synonyms
Tiberal ()
Ornidazolum ()
NSC 95075 ()
Ro 7-0207 ()
Ro7-0207 ()
Ro7-0207, NSC 95075 ()
Ro-70207 ()
NSC-95075 ()
RO-7-0207 ()
Ornidazol ()
Ornidazole-d5 ()
P&D ID
PD000244
CAS
16773-42-5
2747915-64-4
Tags
available
drug
Drug indication
rectum cancer
Amoebiasis
Drug Status
approved
investigational
Max Phase
3.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn¡¯s disease[1][2][3].
PRICE
29
DESCRIPTION
Ornidazole is an orally bioavailable 5-nitroimidazole derivative with antibacterial and antiprotozoal activities. It is a nitroimidazole agent indicated in the treatment of infections such as trichomoniasis, amebiasis, and giardiasis.
(Enamine Bioactive Compounds)
DESCRIPTION
Ornidazole (Tiberal) is a nitroimidazole antiprotozoal agent used in ameba and trichomonas infections. It is partially plasma-bound and also has radiation-sensitizing action.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
17
ChEMBL Drugs
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Enamine Bioactive Compounds
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
32
Molecular Weight
219.04
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
1
Aromatic Ring Count
1
cLogP
0.7
TPSA
81.19
Fraction CSP3
0.57
Chiral centers
1.0
Largest ring
5.0
QED
0.46
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
antibiotic
Bacterial
Parasite
Hedgehog
Pathway
Microbiology/virology
Anti-infection
Stem Cell/Wnt
Source data
