General
Preferred name
PHENFORMIN HYDROCHLORIDE
Synonyms
Phenethylbiguanide hydrochloride ()
Phenformin HCl ()
Phenformin (hydrochloride) ()
Phenformin (NSC-756501) HCl ()
Phenethylbiguanide HCl ()
Dibotin S.R. ()
NSC-23100 ()
Debei ()
P&D ID
PD000242
CAS
834-28-6
21228-47-7
Tags
natural product
drug
available
Drug Status
approved
withdrawn
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
10
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
21
Properties
(calculated by RDKit )
Molecular Weight
241.11
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
5
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
0.66
TPSA
97.78
Fraction CSP3
0.2
Chiral centers
0.0
Largest ring
6.0
QED
0.4
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Membrane Transporter/Ion Channel
PI3K/Akt/mTOR signaling
Autophagy
Epigenetics
PI3K/Akt/mTOR
Target
AMPK
Potassium Channel
Source data
