General
Preferred name
MODALINE SULFATE
Synonyms
Modaline (sulfate) ()
W-3207B ()
Modaline sulphate ()
W 3207B ()
NSC-89277 ()
P&D ID
PD000189
CAS
2856-75-9
Tags
available
drug candidate
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Modaline sulfate is a MAO inhibitor, used in the treatment of depression.
PRICE 29
DESCRIPTION Modaline was a 2-methyl-3-piperidinopyrazine derivative found to inhibit monoamine oxidase (MAO) and showed a curative effect for the anti-depressant. Similar to other MAO inhibitors, it enhanced convulsions induced by tryptamine and hyperthermia induced by dopa. (TargetMol Bioactive Compound Library)
Compound Sets
4
ChEMBL Drugs
CHEMBL2107444
MedChem Express Bioactive Compound Library
HY-B1083
TargetMol Bioactive Compound Library
T0235
The Spectrum Collection
External IDs
13
Properties
(calculated by RDKit )
Molecular Weight
275.09
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
2
Aromatic Ring Count
1
cLogP
1.12
TPSA
103.62
Fraction CSP3
0.6
Chiral centers
0.0
Largest ring
6.0
QED
0.74
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolism
Neuroscience
Neuronal Signaling
Target
Monoamine Oxidase
MAO
Source data