General
Preferred name
PALMIDROL
Synonyms
Palmitoylethanolamide ()
PALMIDROL [5mM] ()
Palmitylethanolamide ()
Palmidrol|N-palmitoylethanolamine ()
Guanfacine extended release ()
N-palmitoylethanolamide, Stief ()
Loramine P 256 ()
N-palmitoylethanolamine ()
N-(2-hydroxyethyl)hexadecanamide ()
Palmitoyl Ethanolamide ()
Palmitoyl Ethanolamide-d4 ()
Palmitoyl Ethanolamide-d5 ()
Levagen ()
Pea (chemical) ()
Palmidrol component of sci-110 palmitoylethanolamide ()
N-(2-hydroxyethyl)-palmitide ()
N(2-hydroxyethyl) palmitide ()
FSD-201 ()
AM 3112 ()
Palmdrol prodes ()
Palmitamide mea ()
NSC-23320 ()
Palmitic monoethanolamide ()
N(2-hydroxyethyl)palmitide ()
Palmitic acid monoethanolamide ()
Impulsin ()
P&D ID
PD000181
CAS
544-31-0
946524-34-1
2117730-91-1
1159908-45-8
Tags
available
drug
Drug indication
Tourette syndrome
Attention deficit hyperactivity disorder
Drug Status
approved
experimental
nutraceutical
investigational
Max Phase
3.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 35
DESCRIPTION Palmitoylethanolamide (Impulsin) is an endogenously fatty acid amide. It has a role as an anti-inflammatory drug, an antihypertensive agent, a neuroprotective agent and an anticonvulsant.Upon administration, palmitoylethanolamide may inhibit the release of pro-inflammatory mediators from activated mast cells.
DESCRIPTION Selective D1-like agonist (Tocris Bioactive Compound Library)
DESCRIPTION Endogenous CB2 cannabinoid receptor agonist (LOPAC library)
DESCRIPTION Selective GPR55 agonist. FAAH and PAA substrate (Tocriscreen Total)
DESCRIPTION Palmitoylethanolamide is an endogenous CB2 cannabinoid receptor agonist and selective GPR55 agonist. (Enamine Bioactive Compounds)
DESCRIPTION PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of Acetylcholine Muscarinic M1 Receptor: Kinetic Measurement of Intracellular Calcium Response. (Class of assay: confirmatory) (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
3
Compound Sets
29
Axon Medchem Screening Library
1211
Cayman Chemical Bioactives
90350
10007824
9000573
9000551
ChEMBL Drugs
CHEMBL417675
Concise Guide to Pharmacology 2017/18
3622
Concise Guide to Pharmacology 2019/20
3622
Concise Guide to Pharmacology 2021/22
3622
Concise Guide to Pharmacology 2023/24
3622
Drug Repurposing Hub
DrugBank
DB14043
DrugCentral
2045
DrugCentral Approved Drugs
2045
DrugMAP
DMB1CZ8
DrugMAP Approved Drugs
DMB1CZ8
DrugMatrix
Enamine Bioactive Compounds
EBC-47502
EU-OPENSCREEN Bioactive Compound Library
EOS100936
Guide to Pharmacology
3622
Ki Database
palmitoylethanolamide
LOPAC library
Mcule NIBR MoA Box Subset
MCULE-1978521574
MedChem Express Bioactive Compound Library
HY-20685
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
palmitoylethanolamide
TargetMol Bioactive Compound Library
0342-0251
The Spectrum Collection
Tocris Bioactive Compound Library
0879
Tocriscreen Total
External IDs
67
Properties
(calculated by RDKit )
Molecular Weight
299.28
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
16
Ring Count
0
Aromatic Ring Count
0
cLogP
4.58
TPSA
49.33
Fraction CSP3
0.94
Chiral centers
0.0
Largest ring
0.0
QED
0.41
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
CB2
Primary Target
GPR55
MOA
Agonist
Cannabinoid CB2 Agonists
Cannabinoid Receptor agonist
Member status
member
Target
CNR2, GPR119, GPR55
GPR55 Agonist
Endogenous Metabolite
Influenza Virus
PPAR
Pathway
Anti-infection
Metabolic Enzyme/Protease
Source data