General
Preferred name
HYMECROMONE
Synonyms
HYMECHROME ()
Cantabiline ()
4-MU ()
4-Methylumbelliferone ()
4-Methylumbelliferone (4-MU) ()
NSC-19026 ()
LM-94 ()
NSC-9408 ()
P&D ID
PD000163
CAS
90-33-5
56275-29-7
Tags
natural product
drug
available
Drug Status
experimental
investigational
approved
Max Phase
Phase 2
Drug indication
Choleretic
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM, used as choleretic and antispasmodic drugs and as a standard for the fluorometric determination of enzyme activity. (BOC Sciences Bioactive Compounds)
Compound Sets
18
AdooQ Bioactive Compound Library
A10015
BOC Sciences Bioactive Compounds
4-methylumbelliferone-cas-90-33-5-item-84-79322
Cayman Chemical Bioactives
29603
ChEMBL Drugs
CHEMBL12208
Drug Repurposing Hub
DrugBank
DB07118
DrugCentral
1401
DrugCentral Approved Drugs
1401
DrugMatrix
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
EOS100832
MedChem Express Bioactive Compound Library
HY-N0187
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
4-Methylumbelliferone(4-MU)
TargetMol Bioactive Compound Library
T1391
The Spectrum Collection
External IDs
45
Properties
(calculated by RDKit )
Molecular Weight
176.05
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
2
Aromatic Ring Count
2
cLogP
1.81
TPSA
50.44
Fraction CSP3
0.1
Chiral centers
0.0
Largest ring
6.0
QED
0.62
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
hyaluronic acid (HA) synthesis
MAOA, MAOB
MOA
monoamine oxidase inhibitor
Source data