General
Preferred name
L-Cycloserine
Synonyms
CYCLOSERINE (L) ()
D-Cycloserine ()
(S)-Cycloserine ()
(S)-4-Amino-3-isoxazolidone ()
LEVCYCLOSERINE ()
Levcicloserina ()
Levcycloserinum ()
(-)-Cycloserine ()
(S)-(-)-Cycloserine ()
(S)-Cycloserine(S)-4-Amino-3-isoxazolidone ()
Levcycloserinum(-)-Cycloserine ()
Levcycloserine, Levcicloserina, Levcycloserinum, (-)-Cycloserine, (S)-Cycloserine ()
NSC-760409 ()
Cycloserine, l- ()
P&D ID
PD000159
CAS
339-72-0
68-41-7
Tags
natural product
drug
available
Drug Status
investigational
approved
Drug indication
Enzyme Inhibitor (gaucher's disease)
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION An analog of the amino acid D-alanine and a component of the racemic drug with the INN cycloserine (see also ). (GtoPdb)
DESCRIPTION Blocks sphingosine biosynthesis by inhibition of ketosphinganine synthetase (LOPAC library)
Compound Sets
14
CeMM library of unique drugs (CLOUD)
ChEMBL Drugs
CHEMBL448864
Concise Guide to Pharmacology 2017/18
9488
Concise Guide to Pharmacology 2019/20
9488
Concise Guide to Pharmacology 2021/22
9488
Concise Guide to Pharmacology 2023/24
9488
DrugBank
DB17627
Guide to Pharmacology
9488
LOPAC library
MedChem Express Bioactive Compound Library
HY-B1122
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
l-cycloserine
TargetMol Bioactive Compound Library
T0710
The Spectrum Collection
External IDs
26
Properties
(calculated by RDKit )
Molecular Weight
102.04
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
1
Aromatic Ring Count
0
cLogP
-1.62
TPSA
64.35
Fraction CSP3
0.67
Chiral centers
1.0
Largest ring
5.0
QED
0.39
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Ketosphinganine synthetase
MOA
bacterial alanine racemase inhibitor
bacterial D-alanine--D-alanine ligase inhibitor
GABA Receptor
Target
Alanine racemase
D-alanylalanine synthetase
D-alanine--D-alanine ligase A
D-alanine--D-alanine ligase
GABA
HIV
Transferase
Pathway
Membrane Transporter/Ion Channel
Neuroscience
Anti-infection
Neuronal Signaling
Source data