General
Preferred name
Sodium fluorophosphate
Synonyms
SODIUM MONOFLUOROPHOSPHATE ()
NSC248 ()
NSC-248 ()
Extra-Strength Aim ()
Mono-Tridin ()
Disodium monofluorophosphate ()
P&D ID
PD000145
CAS
10163-15-2
7631-97-2
Tags
available
drug
inorganic
Drug Status
approved
Max Phase
4.0
Drug indication
Dental Caries
First approval
1986
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
TOXICITY
LD50 Oral: rat-502 -638 mg/kg; LC50 Inhalation: rat-male and female-4 h-> 2,1 mg/l
PRICE
29
DESCRIPTION
Disodium monofluorophosphate (NSC248) is a competitive inhibitor of pyruvate kinase and alkaline phosphatase, which also irreversibly inhibits phosphorylase phosphatase.
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
BOC Sciences Bioactive Compounds
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
Selleckchem Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
32
Molecular Weight
143.94
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
0
Ring Count
0
Aromatic Ring Count
0
cLogP
-7.21
TPSA
63.19
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
0.0
QED
0.25
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
phosphatase inhibitor
Phosphorylase inhibitor
PKM inhibitor
Target
phosphatase
Source data
