General
Preferred name
CARAZOLOL
Synonyms
Conducton ()
Suacron ()
(±)-Carazolol ()
DL-Carazolol ()
Carazolol (hydrochloride) ()
(¡À)-Carazolol ()
BM 51052 ()
BM-51052 ()
BM 51052 (hydrochloride) ()
Carazolol-d7 ()
P&D ID
PD000106
CAS
57775-29-8
51997-43-4
1173021-02-7
Tags
available
drug
Drug indication
Discovery agent
Drug Status
investigational
approved
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
The INN-assigned compound carazolol is a racemic mixture of two enantiomers. The structure shown here does not specify stereochemisty and represents the mixture. The two enantiomers are represented on PubChem by CID 13023332 and CID 13023331. Please note that the PDB entry for this ligand linked to above specifies the S isomer (CID 13023332).
(GtoPdb)
DESCRIPTION
Carazolol is a ¦Â1/¦Â2 adrenoceptor antagonist of high potency used in the research of hypertension. Carazolol is also a potent, selective ¦Â3-adrenoceptor agonist[1].
PRICE
29
DESCRIPTION
Carazolol (Suacron) is a high-affinity antagonist/partial inverse agonist (also referred to as a beta blocker) of the ??-adrenergic receptor.
DESCRIPTION
Carazolol (BM 51052) hydrochloride is a highly potent antagonist of ¦Â1/¦Â2 adrenoceptor. Carazolol hydrochloride is also a potent, selective ¦Â3-adrenoceptor agonist. Carazolol hydrochloride can be used in the research of hypertension[1].
DESCRIPTION
Carazolol is a β-adrenergic receptor antagonist.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
Carazolol (Suacron) is a high-affinity antagonist/partial inverse agonist (also referred to as a beta blocker) of the β-adrenergic receptor.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
3
Organisms
0
Compound Sets
20
BOC Sciences Bioactive Compounds
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
Ki Database
MedChem Express Bioactive Compound Library
Other bioactive compounds
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
34
Molecular Weight
298.17
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
6
Ring Count
3
Aromatic Ring Count
3
cLogP
3.06
TPSA
57.28
Fraction CSP3
0.33
Chiral centers
1.0
Largest ring
6.0
QED
0.66
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
β-adrenergic receptor
Adrenergic Receptor
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Source data
