General
Preferred name
BENDAMUSTINE HYDROCHLORIDE
Synonyms
EP-3101 ()
SDX-105 (Cytostasane) HCl ()
Bendamustine HCl ()
Ribomustin ()
Treanda ()
IMET 3393 ()
Cytostasan ()
2-Benzimidazolinebutryric acid, 1-methyl-5-bis(2-chloroethyl)amino-, hydrochloride ()
SDX-105 ()
WLN: T56 BN DNJ B1 C3VQ GN2G2G &GH ()
1H-Benzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1-methyl-, monohydrochloride ()
2-Benzimidazolebutyric acid, 5-[bis(2-chloroethyl)amino]-1-methyl-, monohydrochloride ()
Bendamustine (hydrochloride) ()
Bendamustine (SDX105) HCl ()
Cytostasane HCl ()
Vivimusta ()
NSC-138783 ()
Belrapzo ()
Bendeka ()
SYBL-0501 ()
SYB L-0501 ()
P&D ID
PD000102
CAS
3543-75-7
Tags
available
drug
Drug indication
leukaemia
Drug Status
approved
Max Phase
4.0
First approval
2008
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Restores mutant p53 activity (Tocris Bioactive Compound Library)
Compound Sets
12
AdooQ Bioactive Compound Library
A10124
Cayman Chemical Bioactives
23693
ChEMBL Approved Drugs
CHEMBL1201734
ChEMBL Drugs
CHEMBL1201734
CZ-OPENSCREEN Bioactive Library
DrugMAP
DMFH15Z
DrugMAP Approved Drugs
DMFH15Z
MedChem Express Bioactive Compound Library
HY-B0077
NIH Approved Oncology Drugs
558674
Selleckchem Bioactive Compound Library
Bendamustine-Hydrochloride
The Spectrum Collection
Tocris Bioactive Compound Library
3681
External IDs
21
Properties
(calculated by RDKit )
Molecular Weight
393.08
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
9
Ring Count
2
Aromatic Ring Count
2
cLogP
3.69
TPSA
58.36
Fraction CSP3
0.5
Chiral centers
0.0
Largest ring
6.0
QED
0.66
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Primary Target
Apoptosis Inducers
Pathway
Apoptosis
Cell Cycle/DNA Damage
Target
DNA alkylator/crosslinker
DNA/RNA Synthesis
Source data