General
Preferred name
TILORONE
Synonyms
Tilorone dihydrochloride ()
Tilorone (dihydrochloride) ()
TILORONE HYDROCHLORIDE ()
Amixin IC ()
NSC-143969 ()
Tilorone hcl ()
Tilorone (hydrochloride) ()
P&D ID
PD000088
CAS
27591-69-1
27591-97-5
Tags
drug candidate
natural product
available
Drug indication
Antiviral
Drug Status
investigational
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
4
Organisms
3
Compound Sets
12
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugMatrix
MedChem Express Bioactive Compound Library
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
37
Properties
(calculated by RDKit )
Molecular Weight
410.26
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
0
Rotatable Bonds
12
Ring Count
3
Aromatic Ring Count
2
cLogP
4.34
TPSA
42.01
Fraction CSP3
0.48
Chiral centers
0.0
Largest ring
6.0
QED
0.44
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
interferon inducer
HIF/HIF Prolyl-Hydroxylase
Influenza Virus
Antiviral,IFN
Indication
influenza A virus infection, diarrhea, hepatitis B, multiple sclerosis, urinary tract infections, virus herpes simplex (HSV), hepatitis C
Disease Area
infectious disease, gastroenterology, neurology/psychiatry
Pathway
Anti-infection
Metabolic Enzyme/Protease
Source data
