General
Preferred name
CHLORMEZANONE
Synonyms
Beserol ()
Trancopal ()
Chlormethazanone ()
NSC-169108 ()
Lyseen New ()
P&D ID
PD000086
CAS
102818-65-5
80-77-3
Tags
natural product
drug
available
Approved by
FDA
First approval
1960
Drug Status
investigational
approved
withdrawn
Drug indication
Anxiety disorder
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION This is a non-benzodiazepine drug. (GtoPdb)
DESCRIPTION Anxiolytic; muscle relaxant (LOPAC library)
DESCRIPTION Prototypic vanilloid receptor agonist (Tocris Bioactive Compound Library)
DESCRIPTION Skeletal muscle relaxant (Tocriscreen Total)
Compound Sets
24
AdooQ Bioactive Compound Library
A10201
Cayman Chemical Bioactives
25716
ChEMBL Approved Drugs
CHEMBL1200714
ChEMBL Drugs
CHEMBL1200714
DrugBank
DB01178
DrugBank Approved Drugs
DB01178
DrugCentral
603
DrugCentral Approved Drugs
603
DrugMAP
DMTWUXR
DrugMAP Approved Drugs
DMTWUXR
DrugMatrix
Enamine BioReference Compounds
Guide to Pharmacology
7323
LOPAC library
MedChem Express Bioactive Compound Library
HY-B0353
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
Chlormezanone(Trancopal)
TargetMol Bioactive Compound Library
T0715
The Spectrum Collection
Tocris Bioactive Compound Library
0456
Tocriscreen Total
Withdrawn 2.0
w150
External IDs
36
Properties
(calculated by RDKit )
Molecular Weight
273.02
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
1
Ring Count
2
Aromatic Ring Count
1
cLogP
1.62
TPSA
54.45
Fraction CSP3
0.36
Chiral centers
1.0
Largest ring
6.0
QED
0.78
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Muscle relaxant
Target
Translocator protein
GABA Receptor
Primary Target
GABAA Receptors
MOA
Benzodiazepine
ATC
M03BB02
Toxicity type
hepatic
Therapeutic Class
Analgesics
Pathway
Membrane Transporter/Ion Channel
Neuronal Signaling
Source data