General
Preferred name
DPCPX
Synonyms
1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE ()
8-Cyclopentyl-1,3-dipropylxanthine ()
CPX ()
PD 116948 ()
PMID28870136-Compound-38 ()
[3H]DPCPX ()
GNF-PF-2224 ()
1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE [DPCPX] ()
[3H]DPCPX ()
P&D ID
PD000085
CAS
102146-07-6
Tags
drug candidate
natural product
available
Drug indication
Discovery agent
Drug Status
investigational
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION A1 selective antagonist (Tocriscreen Total)
DESCRIPTION DPCPX is an A1 adenosine receptor antagonist and could be useful in some physiological studies on cell cultures. (BOC Sciences Bioactive Compounds)
DESCRIPTION Dopamine antagonist with some D4 selectivity; also 5-HT2A/2C antagonist (Tocris Bioactive Compound Library)
DESCRIPTION Selective A1 adenosine receptor antagonist (LOPAC library)
Cell lines
0
Organisms
2
Compound Sets
19
BOC Sciences Bioactive Compounds
dpcpx-cas-102146-07-6-item-53144
Cayman Chemical Bioactives
21972
Concise Guide to Pharmacology 2017/18
386
406
Concise Guide to Pharmacology 2019/20
386
406
Concise Guide to Pharmacology 2021/22
386
406
Concise Guide to Pharmacology 2023/24
386
406
Drug Repurposing Hub
DrugBank
DB12946
DrugMAP
DM26UKN
DM67XSL
DM9GY7O
DrugMatrix
Guide to Pharmacology
386
406
Ki Database
DPCPX
LOPAC library
MedChem Express Bioactive Compound Library
HY-100937
ReFrame library
TargetMol Bioactive Compound Library
T22744
Tocris Bioactive Compound Library
0439
Tocriscreen Total
ZINC Tool Compounds
ZINC000003977757
External IDs
33
Properties
(calculated by RDKit )
Molecular Weight
304.19
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
3
Aromatic Ring Count
2
cLogP
2.36
TPSA
72.68
Fraction CSP3
0.69
Chiral centers
0.0
Largest ring
6.0
QED
0.92
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
A1
Pathway
Adenosine Receptor
GPCR/G protein
Primary Target
Adenosine A1 Receptors
MOA
Antagonist
Adenosine Receptor antagonist
Target
ADORA1, ADORA2A, ADORA2B, ADORA3
Source data