General
Preferred name
EDROPHONIUM CHLORIDE
Synonyms
Edrophonium (chloride) ()
Edrophone Chloride ()
Edrophonium Chloride Preservative Free ()
Reversol ()
Camsilon ()
Enlon ()
Antirex ()
Tensilon Preservative Free ()
Edrophonii chloridum ()
Tensilon ()
NSC-759577 ()
P&D ID
PD000063
CAS
116-38-1
312-48-1
Tags
available
drug
Drug Status
approved
Max Phase
Phase 4
Drug indication
Diagnostic Aid (myasthenia gravis)
Antidote (to curare principles)
First approval
1951
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Acetylcholinesterase inhibitor
(LOPAC library)
DESCRIPTION
Edrophonium chloride is a reversible Acetylcholinesterase inhibitor which is effective in avoiding the decomposition of the neurotransmitter acetylcholine competitively so that could be commonly used in the diagnosis of myasthenia gravis and other sorts o
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
14
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
DrugMatrix
EU-OPENSCREEN Bioactive Compound Library
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NIH Clinical Collections (NCC)
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
20
Molecular Weight
201.09
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
-1.02
TPSA
20.23
Fraction CSP3
0.4
Chiral centers
0.0
Largest ring
6.0
QED
0.61
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Acetylcholinesterase
Pathway
Neuroscience
Neuronal Signaling
Target
AChE
Cholinesterase (ChE)
AChR
Solubility
DMSO: 31 mg/mL
Source data
