General
Preferred name
VERAPAMIL HYDROCHLORIDE
Synonyms
(±)-Verapamil hydrochloride ()
(¡À)-Verapamil hydrochlorid ()
(??)-Verapamil hydrochlorid ()
Verapamil HCl ()
Manidon ()
Calcan hydrochloride ()
VERAPAMIL ()
Verapamyl hydrochloride ()
Verapamil (hydrochloride) ()
(±)-Verapamil (hydrochloride) ()
CP-16533-1 (hydrochloride) ()
Verapamil (CP-16533-1) HCl ()
(¡À)-Verapamil hydrochloride ()
Cordilox MR 240 ()
Vertab SR 240 ()
Calan ()
Ranvera MR ()
Securon Mid ()
Half Securon SR ()
Zolvera ()
Covera ()
NSC-657799 ()
Covera-HS ()
Securon ()
Verapress MR 240 ()
LU-20175 ()
Securon IV ()
Manidon SR ()
Berkatens ()
Verapamili hydrochloridum ()
Geangin ()
Univer ()
Cordilox ()
Ethimil MR 240 ()
Verelan ()
Securon SR ()
Cordilox I.V. ()
Verelan pm ()
Isoptin Sr ()
Isoptin ()
CP-16533-1 ()
Vera-Til SR ()
Calan Sr ()
NSC-272366 ()
Verapamil (hydrochloride) ()
P&D ID
PD000051
CAS
152-11-4
38176-10-2
52-53-9
Tags
natural product
drug
available
Drug Status
approved
Max Phase
Phase 4
Drug indication
Cardiac Depressant (anti-arrhythmic)
Anti-Anginal
First approval
1981
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION L-type Ca2+ channel modulator; adrenoceptor antagonist; antiarryhthmic; cardiac depressant; coronary vasodilator (LOPAC library)
DESCRIPTION P2X antagonist (Tocris Bioactive Compound Library)
Cell lines
2
Organisms
2
Compound Sets
14
Axon Medchem Screening Library
3452
Cayman Chemical Bioactives
14288
ChEMBL Approved Drugs
CHEMBL1280
ChEMBL Drugs
CHEMBL1280
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
EOS101717
Ki Database
VERAPAMIL
LOPAC library
MedChem Express Bioactive Compound Library
HY-A0064
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
verapami-hcl
TargetMol Bioactive Compound Library
T1010
The Spectrum Collection
Tocris Bioactive Compound Library
0654
External IDs
19
Properties
(calculated by RDKit )
Molecular Weight
490.26
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
0
Rotatable Bonds
13
Ring Count
2
Aromatic Ring Count
2
cLogP
5.51
TPSA
63.95
Fraction CSP3
0.52
Chiral centers
1.0
Largest ring
6.0
QED
0.37
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
L-type
Pathway
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
Target
Calcium Channel
Ca channel antagonist
Cytochrome P450
P-glycoprotein
Calcium Channel,P450 (e.g. CYP17),P-gp
Primary Target
CaV1.x Channels (L-type)
MOA
Blocker
Source data