General
Preferred name
ETOFYLLINE
Synonyms
7-HYDROXYETHYLTHEOPHYLLINE ()
7-(¦Â-Hydroxyethyl)theophylline ()
7-(β-Hydroxyethyl)theophylline ()
Aethophyllinum ()
7-Theophyllineethanol ()
Oxyphylline ()
Cordalin ()
7-(??Hydroxyethyl)theophylline ()
BETA-HYDROXYETHYL THEOPHYLLINE ()
Aethophyllinum, Cordalin, Oxyphylline ()
Etofilina ()
Phyllocormin n ()
Theophylline related compound f ()
Soluphylline ()
Doxophylline metabolite m4 ()
NSC-113373 ()
Theophylline isopropanolamine ()
Oxyphyllin ()
Frekaphyllin ()
Theopropanol ()
KT-200G ()
7-(?-Hydroxyethyl)theophylline ()
7-(?-Hydroxyethyl)theophylline-d6 ()
P&D ID
PD000042
CAS
519-37-9
Tags
available
drug
Drug indication
Discovery agent
Drug Status
approved
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Etofylline (7-(¦Â-Hydroxyethyl) theophylline) is an oral bronchodilator with anti-inflammatory effects. Etofylline inhibits phosphodiesterase and prevents the degradation of cAMP (cyclic adenosine monophosphate), leading to smooth muscle relaxation, reducing inflammatory responses and improving respiratory function. Etofylline affects the development of zebrafish embryos[1][2][3].
PRICE
29
DESCRIPTION
Etofylline is a N-7-substituted derivative of theophylline, a smooth muscle relaxant. Etofylline is used to relieve bronchoconstriction. It may act as a phosphodiesterase inhibitor and adenosine receptor antagonist.
(Enamine Bioactive Compounds)
DESCRIPTION
Etofylline (Oxyphylline) is used for difficulty in breathing, asthma, breathing difficulty and other conditions.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
15
ChEMBL Drugs
Drug Repurposing Hub
DrugCentral
DrugCentral Approved Drugs
DrugMAP
Enamine Bioactive Compounds
Enamine BioReference Compounds
Ki Database
MedChem Express Bioactive Compound Library
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
31
Molecular Weight
224.09
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
2
cLogP
-1.57
TPSA
82.05
Fraction CSP3
0.44
Chiral centers
0.0
Largest ring
6.0
QED
0.67
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
asthma, bronchitis
Target
ADORA1
Phosphodiesterase (PDE)
MOA
Adenosine Receptor antagonist
Pathway
Metabolic Enzyme/Protease
Source data
