General
Preferred name
PHENAZINE-1-CARBOXYLIC ACID
Synonyms
Tubermycin B ()
P&D ID
PD143313
CAS
2538-68-3
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Phenazine-1-carboxylic acid is an antifungal agent. Additionally, Phenazine-1-carboxylic acid exhibits anticancer activity by inducing apoptosis in cancer cells through the regulation of ROS generation. Phenazine-1-carboxylic acid can upregulate the expression of IL-8 and ICAM-1 while inhibiting the release of RANTES and MCP-1, demonstrating its potential immunomodulatory effects. Phenazine-1-carboxylic acid holds significant research value in the areas of anti-infection, anticancer, and immune response modulation[1][2][3][4].
PRICE 29
DESCRIPTION Phenazine-1-carboxylic acid shows strong antifungal activity against all phytopathogenic fungi, inhibiting the fungal growth by about 90-100%. Phenazine-1-carboxylic acid could be used to compete with other phytopathogenic fungi that attack grapevine (TargetMol Bioactive Compound Library)
Cell lines
2
Organisms
0
Compound Sets
4
Cayman Chemical Bioactives
33659
MedChem Express Bioactive Compound Library
HY-33037
Selleckchem Bioactive Compound Library
phenazine-1-carboxylic-acid
TargetMol Bioactive Compound Library
TN7105
External IDs
21
Properties
(calculated by RDKit )
Molecular Weight
224.06
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
1
Ring Count
3
Aromatic Ring Count
3
cLogP
2.48
TPSA
63.08
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.64
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Pathway
Microbiology/virology
Anti-infection
Target
Fungal
Antifungal
Source data