General
Preferred name
RU 24969
Synonyms
RU 24969 hemisuccinate ()
RU-24969 ()
RU 24969 (succinate) ()
RU-24969 (succinate) ()
P&D ID
PD047960
CAS
107008-28-6
66611-27-6
74163-68-1
66611-26-5
Tags
available
drug candidate
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Selective D2-like antagonist
(Tocris Bioactive Compound Library)
DESCRIPTION
5-HT1B/1A agonist
(Tocriscreen Total)
DESCRIPTION
RU 24969 hemisuccinate is a potent and selective agonist at the 5-HT1A and 5-HT1B receptors. It is centrally active following systemic administration.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
17
AdooQ Bioactive Compound Library
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
Drug Repurposing Hub
DrugMAP
DrugMatrix
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
Ki Database
NIH Clinical Collections (NCC)
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
Tocriscreen Total
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
41
Molecular Weight
228.13
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
2
cLogP
2.55
TPSA
37.05
Fraction CSP3
0.29
Chiral centers
0.0
Largest ring
6.0
QED
0.83
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Target
5-HT1A
5-HT1B
HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, HTR6
5-HT Receptor
Primary Target
5-HT1A Receptors
MOA
Agonist
5-HT1A Receptor Agonists
5-HT1B Agonists
serotonin receptor agonist
Member status
virtual
Source data
