General
Preferred name
butyric acid
Synonyms
Butyric acid ()
sodium-butyrate ()
BUTANOIC ACID ()
Sodium n-butyrate ()
NSC-8415 ()
N-butanoic acid ()
Normal butyric acid ()
Butyrate ()
FEMA NO. 2221 ()
N-butyric acid ()
Butyricum acidum ()
Butyric Acid-d7 ()
P&D ID
PD006806
CAS
107-92-6
461-55-2
73607-83-7
Tags
drug candidate
natural product
available
Drug indication
Discovery agent
Drug Status
experimental
investigational
Max Phase
Phase 2
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Butyric acid inhibits class I and II HDACs.
DESCRIPTION Butyric acid (butyrate) inhibits class I and II HDACs . (GtoPdb)
Compound Sets
13
Cayman Chemical Bioactives
29408
ChEMBL Drugs
CHEMBL14227
Concise Guide to Pharmacology 2017/18
1059
Concise Guide to Pharmacology 2019/20
1059
Concise Guide to Pharmacology 2021/22
1059
Concise Guide to Pharmacology 2023/24
1059
Drug Repurposing Hub
DrugBank
DB03568
DrugMAP
DMTAJP7
Guide to Pharmacology
1059
JUMP-Target 1 Compound Set
264
Other bioactive compounds
ReFrame library
External IDs
62
Properties
(calculated by RDKit )
Molecular Weight
88.05
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
0
Aromatic Ring Count
0
cLogP
0.87
TPSA
37.3
Fraction CSP3
0.75
Chiral centers
0.0
Largest ring
0.0
QED
0.54
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
Endogenous Metabolite
HDAC inhibitor
Pathway
Metabolic Enzyme/Protease
Target
Human Endogenous Metabolite
BCHE, FFAR2, FFAR3, HDAC1, HDAC2, HDAC3, HDAC8
FFAR2
Source data